Emerging pathogenic links between microbiota and the gut-lung axis

Title: Emerging pathogenic links between microbiota and the gut-lung axis
Creator: Budden, Kurtis F.; Gellatly, Shaan L.; Wood, David L. A.; Cooper, Matthew A.; Morrison, Mark; Hugenholtz, Philip; Hansbro, Philip M.
Relation: Funding BodyNHMRCGrant Number1079187 http://purl.org/au-research/grants/nhmrc/GNT1079187
Relation: Nature Reviews Microbiology Vol. 15, Issue 1, p. 55-63
Publisher Link: http://dx.doi.org/10.1038/nrmicro.2016.142
Publisher: Nature Publishing Group
Resource Type: journal article
Date: 2017
Description: The microbiota is vital for the development of the immune system and homeostasis. Changes in microbial composition and function, termed dysbiosis, in the respiratory tract and the gut have recently been linked to alterations in immune responses and to disease development in the lungs. In this Opinion article, we review the microbial species that are usually found in healthy gastrointestinal and respiratory tracts, their dysbiosis in disease and interactions with the gut-lung axis. Although the gut-lung axis is only beginning to be understood, emerging evidence indicates that there is potential for manipulation of the gut microbiota in the treatment of lung diseases.
Subject: microbiota; immune system; dysbiosis; immune responses; gut-lung axis
Identifier: http://hdl.handle.net/1959.13/1391960
Identifier: uon:33310
Identifier: ISSN:1740-1526
Language: eng
Full Text
Reviewed

Collections

Goal 3: Good Health and Well-Being

		Thumbnail	File	Description	Size	Format
View Details Download			ATTACHMENT02	Author final version	900 KB	Adobe Acrobat PDF	View Details Download